Investigación FAME UACh

Dra. Claudia Torres-Farfan | Investigadora UACh

Dra. Claudia Torres-Farfan

Publicaciones Relevantes de los últimos 10 años

  1. Vilches N, Spichiger C, Mendez N, Abarzua-Catalan L, Galdames HA, Hazlerigg DG, Richter HG, Torres-Farfan C. Gestational Chronodisruption Impairs Hippocampal Expression of NMDA Receptor Subunits Grin1b/Grin3a and Spatial Memory in the Adult Offspring. PLoS One. 2014; 9:e91313.
  2. Galdames HA, Torres-Farfan C, Spichiger C, Mendez N, Abarzua-Catalan L, Alonso-Vazquez P, Richter HG. Impact of gestational chronodisruption on fetal cardiac genomics. J Mol Cell Cardiol. 2014; 66:1-11.
  3. Serón-Ferré M, Forcelledo ML, Torres-Farfan C, Valenzuela FJ, Rojas A, Vergara M, Rojas-Garcia PP, Recabarren MP, Valenzuela GJ. Impact of chronodisruption during primate pregnancy on the maternal and newborn temperature rhythms. PloSOne. 2013; 8:e57710.
  4. Mendez N, Abarzua-Catalan L, Vilches N, Galdames HA, Spichiger C, Richter HG, Valenzuela GJ, Seron-Ferre M, Torres-Farfan C. Timed maternal melatonin treatment reverses circadian disruption of the fetal adrenal clock imposed by exposure to constant light. PLoS One. 2012; 7:e42713.
  5. Serón-Ferré M, Mendez N, Abarzua-Catalan L, Vilches N, Valenzuela FJ, Reynolds HE, Llanos AJ, Rojas A, Valenzuela GJ, Torres-Farfan C. Circadian rhythms in the fetus. Mol Cell Endocrinol. 2012; 349:68-75.
  6. Torres-Farfan C, Mendez N, Abarzua-Catalan L, Vilches N, Valenzuela GJ, Seron-Ferre M. A circadian clock entrained by melatonin is ticking in the rat fetal adrenal. Endocrinology. 2011; 152:1891-900.
  7. Herrera EA, Ebensperger G, Riquelme R, Díaz M, Reyes V, Torres-Farfan C, Llanos A. Cardiopulmonary response to stepwise oxygenations in newborn sheep from different altitudes Avances en Ciencias Veterinarias. 2011; 26:1-11.
  8. Campino C, Valenzuela FJ, Torres-Farfan C, Reynolds HE, Abarzua-Catalan L, Arteaga E, Trucco C, Guzmán S, Valenzuela GJ, Seron-Ferre M. Melatonin exerts direct inhibitory actions on ACTH responses in the human adrenal gland. Horm Metab Res. 2011; 43:337-42.
  9. Torres-Farfan C, Abarzua-Catalan L, Valenzuela FJ, Mendez N, Richter HG, Valenzuela GJ, Serón-Ferré M. Cryptochrome 2 expression level is critical for adrenocorticotropin stimulation of cortisol production in the capuchin monkey adrenal. Endocrinology. 2009; 150:2717-22.
  10. Campino C, Valenzuela F, Arteaga E, Torres-Farfán C, Trucco C, Velasco A, Guzmán S, Serón-Ferré M. [Melatonin reduces cortisol response to ACTH in humans]. Rev Med Chil. 2008; 136:1390-7.
  11. Torres-Farfan C, Valenzuela FJ, Mondaca M, Valenzuela GJ, Krause B, Herrera EA, Riquelme R, Llanos AJ, Seron-Ferre M. Evidence of a role for melatonin in fetal sheep physiology: direct actions of melatonin on fetal cerebral artery, brown adipose tissue and adrenal gland. J Physiol. 2008; 586:4017-27.
  12. Valenzuela FJ, Torres-Farfan C, Richter HG, Mendez N, Campino C, Torrealba F, Valenzuela GJ, Serón-Ferré M. Clock gene expression in adult primate suprachiasmatic nuclei and adrenal: is the adrenal a peripheral clock responsive to melatonin? Endocrinology. 2008; 149:1454-61.
  13. Richter HG, Torres-Farfan C, Garcia-Sesnich J, Abarzua-Catalan L, Henriquez MG, Alvarez-Felmer M, Gaete F, Rehren GE, Seron-Ferre M. Rhythmic expression of functional MT1 melatonin receptors in the rat adrenal gland. Endocrinology. 2008; 149:995-1003.
  14. Seron-Ferre M, Valenzuela GJ, Torres-Farfan C. Circadian clocks during embryonic and fetal development. Birth Defects Res C Embryo Today. 2007; 81:204-14.
  15. Torres-Farfan C, Valenzuela FJ, Ebensperger R, Méndez N, Campino C, Richter HG, Valenzuela GJ, Serón-Ferré M. Circadian cortisol secretion and circadian adrenal responses to ACTH are maintained in dexamethasone suppressed capuchin monkeys (Cebus apella). Am J Primatol. 2008; 70:93-100.
  16. Dinet V, Ansari N, Torres-Farfan C, Korf HW. Clock gene expression in the retina of melatonin-proficient (C3H) and melatonin-deficient (C57BL) mice. J Pineal Res. 2007; 42:83-91.
  17. Torres-Farfan C, Valenzuela FJ, Germain AM, Viale ML, Campino C, Torrealba F, Valenzuela GJ, Richter HG, Serón-Ferré M. Maternal melatonin stimulates growth and prevents maturation of the capuchin monkey fetal adrenal gland. J Pineal Res. 2006; 41:58-66.
  18. Torres-Farfan C, Rocco V, Monsó C, Valenzuela FJ, Campino C, Germain A, Torrealba F, Valenzuela GJ, Seron-Ferre M. Maternal melatonin effects on clock gene expression in a nonhuman primate fetus. Endocrinology. 2006; 147:4618-26.
  19. Torres-Farfan C, Serón-Ferré M, Dinet V, Korf HW. Immunocytochemical demonstration of day/night changes of clock gene protein levels in the murine adrenal gland: differences between melatonin-proficient (C3H) and melatonin-deficient (C57BL) mice. J Pineal Res. 2006; 40:64-70
  20.  Richter HG, Torres-Farfán C, Rojas-García PP, Campino C, Torrealba F, Serón-Ferré M. The circadian timing system: making sense of day/night gene expression. Biol Res. 2004; 37:11-28.
  21. Torres-Farfan C, Richter HG, Germain AM, Valenzuela GJ, Campino C, Rojas-García P, Forcelledo ML, Torrealba F, Serón-Ferré M. Maternal melatonin selectively inhibits cortisol production in the primate fetal adrenal gland. J Physiol. 2004 ;554(Pt 3):841-56.
  22. Torres-Farfan C, Richter HG, Rojas-García P, Vergara M, Forcelledo ML, Valladares LE, Torrealba F, Valenzuela GJ, Serón-Ferré M. mt1 Melatonin receptor in the primate adrenal gland: inhibition of adrenocorticotropin-stimulated cortisol production by melatonin. J Clin Endocrinol Metab. 2003; 88:450-8.